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This week we have an interesting case from Dr Slavko Doslo. A 40-year-old female with concerns about a lonely lesion noted on her foot.
Please review and describe the clinical and dermoscopic images. What is your evaluation, and differential diagnosis? What would you do?
If you have an interest in dermoscopy and skin cancer medicine, don’t miss the International Dermoscopy Society’s 5th World Congress of Dermoscopy, to be held in Thessaloniki, Greece from 14 to 16 June 2018.
The Congress will bring together passionate dermoscopists from around the globe, from novice researchers to experienced clinicians. It offers a great opportunity for medical professionals interested in skin cancer to learn about the latest research in dermoscopy from inspirational thought leaders in the field. Continue reading “HealthCert Recommends: The IDS 5th World Congress of Dermoscopy”
This month, we have a really interesting and relevant research letter to review and consider, concerning the proportion of melanomas managed by GPs in Australia. This was published in the Australasian Journal of Dermatology by Wu et al. I noted it in part because it referenced some research that I did a decade ago (how time flies)! The authors used Medicare billing data to look at trends in melanoma excision over time across Australia. Continue reading “Proportion of Melanomas Managed by GPs in Australia”
This week we have another interesting case from Dr Slavko Doslo. A 61-year-old female with concerns about pigmented lesion on nipple.
Please review and describe the clinical and dermoscopic images. What is your assessment, and what would you do? Continue reading “Case discussion: How would you treat this patient? [08 January]”
A multi-centre study has explored the prevalence of melanoma on hairy scalps in comparison to bald scalps. Associate Professor Giuseppe Argenziano explains in this skin cancer update video that – while around 76 percent of scalp melanomas are found on people with thinning or no hair – a quarter appear on people with hairy scalps.
Scalp melanoma can be aggressive and has a poorer prognosis compared to melanoma found elsewhere on the body, because scalp melanoma is generally thicker at the time of diagnosis. It also looks different depending on where it is located on the scalp itself, making it trickier to identify. Continue reading “Skin Cancer Update with A/Prof Giuseppe Argenziano [January 2018]”
Although the risk of relapse of patients with thin melanoma is regraded low, a significant and steadily increasing proportion of early-stage cutaneous melanoma patients relapse and die of their melanoma. In fact, 25 percent of mortality is caused by cutaneous melanomas smaller than 1 millimetre in thickness. These high-risk patients cannot be detected, so far, by conventional prognostic methods.
At the 9th World Congress of Melanoma and 14th International Congress of the Society for Melanoma Research, a team of German scientists presented research to address this problem. They had previously identified a prognostic gene signature expressed in cutaneous melanoma and adjacent stroma. A validated signature-based gene expression risk score predicts patient survival and need for adjuvant therapy. Continue reading “Detecting Thin Melanoma”
BRAF mutation is associated with sentinel lymph node positivity and central nervous system metastasis in patients with primary cutaneous melanoma, according to new research.
The findings were presented at the 9th World Congress of Melanoma and 14th International Congress of the Society for Melanoma Research.
A cohort of 1,544 patients with primary cutaneous melanoma were analysed to determine whether BRAF-mutant, NRAS-mutant and wild-type tumours differ in their sites of visceral metastasis. Continue reading “BRAF Mutation Associated With Central Nervous System Metastasis in Melanoma Patients”
Does ultrasound-based follow-up improve survival outcomes of patients with stage 1-2 melanoma? A study in the European Journal of Cancer compared the efficacy of an ultrasound-based follow-up with a clinical follow-up to determine whether ultrasonography of the regional lymph nodes and abdomen improves melanoma-specific survival.
Different protocols have been used to follow up melanoma patients in stage 1-2 but there is no consensus on the complementary tests that should be requested, or the appropriate intervals between visits. Continue reading “Does ultrasound-based follow-up improve survival of melanoma patients?”
How does a family history of melanoma affect the risk of developing subsequent skin cancers in patients with multiple primary melanomas?
It has been noted that patients with multiple primary melanomas have worse outcomes than those with single primary melanomas. Continue reading “How does a family history of melanoma impact patients with multiple primary melanomas?”
A recent study explored the health-related quality of life in recurrence-free melanoma patients, with a focus on the association between melanoma-related limb lymphoedema and quality of life.
The study – which was recently published in European Journal of Cancer – enlisted 431 melanoma patients who had undergone wide local excision and axillary or inguinal sentinel lymph node biopsy and/or complete lymph node dissection. No patients had had recurrence of the disease or received any adjuvant radiotherapy. Continue reading “Impact of Melanoma-Related Lymphoedema on Quality of Life”